Hi @ydhanabalan
Use Path Like This
"C:\Users\username\AppData\Local\Programs\Python\Python310"
Target: x64
Version: Auto
For Me this worked because i was using 1.6.0 Python Activities. With Python 3.6.8. Also Update package to latest version which supports latest python version
Check this also
https://forum.uipath.com/t/error-initializing-python-engine/334238/4?u=aj_ask
Hope this helps