Hi @Darth
I am not aware of a feature that would strictly do it, but I registered it as a feature request and it might get implemented in the future 
(no promises here, as the product team has a lot to prioritize already 
).
However, given how UiPath software works, there is always a valid workaround. I hope other users will chime in with possible solutions
You could give a basic explanation of the Mutex Exclusion and maybe someone would be able to reproduce it with available tools.