Hi,
I normally use the Read Range or Excel Scope, manipulate my datatable, then output the table back on the file.
However, if you are wanting to use another method, you can try the Start Process activity.
in the application field you put the full path of Microsoft Excel, and in the arguments you put the filename. It’s just like using command line so you’ll need quotes around the argument
For example,
“…\EXCEL.exe”
“”“”+filepath+“”“”