Mail not been sent in outlook showing below error

Help Apps
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1

Error is [0x80004005-0x000004b9-0x00000501].
Submit-Message failed: message id(1), failure enum(6), HResult(0x80004005), EC(0).

Outlook
Outlook785×441 64.8 KB

2

@Manju_Reddy_Kanughula ,

How are you sending email?

Thanks,
AK

3

Through send outlook mail messages

4

Can you trying using SMTP?