This definitely sounds like group policy (aka GPO) periodically updating on your machine (hence why it only happens every few days, as your machine resyncs itself) and changing some settings.
The “toggle UI ability is greyed out” (or sometimes, extension does not appear at all, even if installed) is usually a giveaway that something is being forced via GPO.
Generally, Chrome GPOs are set via Registry settings, so you can see them via Registry Editor (aka regedit.msc). Chrome settings will usually be under “Computer\HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Google\Chrome”.
DISCLAIMER for readers: Do NOT change anything in the registry, unless you know what you’re doing!
Google’s reference list can be found here: Chrome Enterprise Policy List & Management | Documentation . Search “extension” for the ones likely relevant to your issue.
There’s some documentation around Chrome policies for UiPath here: Chrome Group Policies
Would recommend (1) browsing under that registry location to see what’s set on your computer (or check in Chrome via “chrome://policy”), (2) read about any settings you find on the Google documentation page, (3) discuss with your corporate security team if you need an exception or changed settings because something they have set is conflicting with your installed extension.