Regular Expression Set containing line break

How do I write a regular expression containing the character for line break?

should be contained within a character set e.g. “[,.:;/]” because I want to replace these characters

Depends on your source, you’d be looking for \r, \n, \n\r.
Alternatively could also use String.Replace with VbCr, VbLf, VbCrLf if you are not restricted to just Regex.