You can simply use the Remove duplicates activity, it is the excel activity.
Check the below workflow for Excel activities,
→ Use the Excel Process scope activity and insert the Use excel file activity inside of it and pass the file path.
→ Inside Use excel file activity insert the Remove duplicates activity.
→ Specify the range in the range field, check the Compare individual column option and Click on add Column and give the column name with in the double quotes.
Check the below workflow for better understanding,