Sub Macro1()
    Columns("E:E").Select
    Selection.FormatConditions.AddUniqueValues
    Selection.FormatConditions(Selection.FormatConditions.Count).SetFirstPriority
    Selection.FormatConditions(1).DupeUnique = xlDuplicate
    With Selection.FormatConditions(1).Interior
        .PatternColorIndex = xlAutomatic
        .Color = 255
        .TintAndShade = 0
    End With
End Sub