SMTP Emails and Automated Responses

We are working on an automation that sends out emails via SMTP. We need to know if we receive any response emails such as email no longer valid, recipient out of office etc.

How can this be accomplished?

Well, maybe consider creating a folder called like Replies and a rule to move only those replies to there, the robot can read that to see if you got any…

The challenge is that using SMTP to my knowledge we don’t receive the replies. Does anyone know how to receive replies using SMTP?