Hi,
Don’t know why you used trim .
1.Here is the way to open the application
Right click on SIM.exe and send to desktop (to create a shortcut) then assign shortcut key ex(ctl+alt+s) then use send hotkey activity and pass the shortcut key it will launch your application.
2. Either use start process or open application and pass the "C:\Program Files (x86)\JDA\JDA Advanced Warehouse Replenishment\SIM.exe" in the property. I will work.
after some tinkering i found the correct file to open the app and pointed uipath to it,turns out the app has an specific shortcut so i just created a short cut to that and it worked