Issue while run the process in remote machine

From my local machine I have connected the another VM (through VPN) and then run the process that deployed in the remote machine.While running that process, the One note opens automatically in my local. What is the reason for that and how can I resolve this issue?

What do you mean by the One Note? If the bot is running on the VM (so you have clicked the run button on the UiPath Robot interface from the system tray) then the job should run in the VM only:

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A tip I find useful is after you’ve hit “Run” in the above panel - not showing for me as this laptop isn’t connected to Orchestrator or bots - then quickly click back into your main PC screen if you are running multiple monitors and then you can keep working like usual without interfering with it by moving the mouse etc.