Please check Conversion from integer to Excel Column (Base 26) A-Z/AA/AAA etc - #11 by jessbrian for the conversion of numbers(coresponding to the column number) to letters (coresponding to the column names used in excel).
And for the read and write activities, if ColVar contains a letter, and RowVar contains a number, you can use them in that field like ColVar+RowVal (carefull at spaces).