Hi @mark_rajkumar1 ,
An Alternate using Linq :
DT = DT.AsEnumerable.Where(Function(x)Not(x.ItemArray.All(Function(x)String.IsNullOrWhiteSpace(x.ToString)))).CopyToDatatable
Here, DT
is your Datatable variable.
For Handling Errors related to Direct CopyToDatatable, Check the below post :